Oxidized Carbon Black as an Activator of ... - ACS Publications

Nov 14, 2017 - cheap and metal-free catalysts has attracted much attention1−6 ... much less studied for cheaper and easily available carbon black ...
0 downloads 10 Views 1MB Size
This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.

Article Cite This: ACS Omega 2017, 2, 7862-7867

http://pubs.acs.org/journal/acsodf

Oxidized Carbon Black as an Activator of Transesterification Reactions under Solvent-Free Conditions Maria Rosaria Acocella,* Mario Maggio, Chiara Ambrosio, Noemi Aprea, and Gaetano Guerra* Department of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II, 132, Fisciano, Salerno 84084, Italy S Supporting Information *

ABSTRACT: A metal-free procedure for oxidation of carbon black (CB), under mild and ecofriendly conditions, is described. The procedure, based on 5/1 w/w H2O2/H2SO4, when applied to high-surface-area CB, leads to oxidation contents (O/C = 0.66) comparable to those obtained for graphite with the more aggressive and metal-based Hummers method (O/C 0.63). Oxidized nanocarbons are able to activate transesterification reactions under solvent-free conditions. Activation of transesterification reactions is much more effective by oxidized CB than by graphene oxide.

1. INTRODUCTION The large diffusion of carbon-based materials as heterogeneous catalysts is essentially due to their unique set of properties such as physical stability, accessibility, easy handling, and recyclability. Recently, the emerging application of carbon materials as cheap and metal-free catalysts has attracted much attention1−6 mainly to graphite oxide (GO) and exfoliated GO (eGO, i.e., graphene oxide), as a solid acid in Friedel−Crafts7,8 or azaMichael additions,9 Mukaiyama−Michael addition,10 Mukaiyama aldol reaction,11 and in esterification reaction,12 meeting the need of environmentally benign alternatives to current organic chemical processes. Oxidation procedures, widely explored for graphite,13−15 are much less studied for cheaper and easily available carbon black (CB), obtained by incomplete combustion of hydrocarbon or as a byproduct of many industrial processes.16 The well-known Hummers procedure,15 effective for converting graphite into GO, is also effective for converting CB into oxidized CB (oCB). In particular, high oxidation degrees (O/C > 0.8) can be achieved starting from the high-surface-area CB (SACB ≈ 150 m2/g).17 oCB exhibits functional groups (epoxides, carboxylic acids, and hydroxyl groups),17 which are expected to promote many reactions. In particular, the large amount of hydroxyl and carboxyl groups suggests oCB as a candidate as a carbocatalyst for many important reactions. Although the Hummers procedure is effective with both graphite and CB samples leading to high-functionalized carbon materials, the notnegligible amount of metal impurities could affect the oxidized materials, generating new active sites for catalytic reactions.6 In the first part of this paper, we present a complete metalfree procedure for oxidation of CB under mild and ecofriendly conditions, which is effective on high-surface-area CB. This procedure leads to oCB, with sulfur contents comparable to those obtained by the Hummers method. © 2017 American Chemical Society

In the second part of the paper, we evaluate the catalytic activity of different oxidized carbon materials in transesterifications (Scheme 1), that is, relevant organic reactions Scheme 1. General Scheme for Transesterification Reaction

often used for laboratory and industrial applications. In fact, the ester-to-ester transformation is particularly useful when the parent carboxylic acids are labile and difficult to isolate. Moreover, some esters are readily or commercially available, more stable, and easy to handle, and thus they conveniently serve as starting materials in transesterification. Transesterification is relevant not only for organic synthesis but also for the production of esters of oils and fats16 as well as for many kinds of polymerizations, for example, ring opening of lactones18 or for curing of alkyd resins.19 To accelerate the reaction, an acid or a base catalyst is often employed and it can be homogeneous20 or heterogeneous21−23 with the system. Many disadvantages of the homogeneous catalysts, such as corrosivity, sensitiveness to purity of reactants, and difficulty in their removal from generated wastewaters, limit their application and drive the catalyst choice toward the heterogeneous ones. The use of solid catalysts for chemical transformation has received much attention owing to their properties such as easy recovery, reuse, and environmental friendliness. In particular, the possibility to catalyze the reaction under acidic condition was particularly explored for biodiesel Received: July 17, 2017 Accepted: August 25, 2017 Published: November 14, 2017 7862

DOI: 10.1021/acsomega.7b01007 ACS Omega 2017, 2, 7862−7867

ACS Omega

Article

Table 1. Elemental Analysis of the Oxidized Carbon Materials

a

starting material

oxidation method

sample name

C (wt %)

H (wt %)

O (wt %)

S (wt %)

O/C (w/w)

CBa CBa graphiteb graphite graphiteb

Hummers H2O2/H2SO4 5/1, v/v Hummers Hummers H2O2/H2SO4 5/1, v/v

oCB-1 oCB-2 GO eGO

50.3 55.4 56.1 59.4 88

2.3 1.7 1.2 0.6 0.7

41.7 36.6 39.8 37.1 11.6

5.4 6.1 2.7 2.6

0.83 0.66 0.71 0.62 0.13

CB has a surface area of 151 m2/g. bGraphite has a surface area of 330 m2/g.

production where the inorganic solid acids, such as zeolite,21 niobic acid,22 and sulfonated zirconia,24 were used. Strongly acidic ion-exchange resins, such as, Amberlyst 15 and Nafion NR50,25 can also be effective, although their applications are limited by their high cost and low stability. We herein report the activation, under solvent-free conditions, of many transesterification reactions by several oxidized carbon materials: GO, graphene oxide (i.e., eGO), oCB by Hummers procedure (oCB-1), and oCB by the H2O2/ H2SO4 mixture (oCB-2). oCB is revealed to be a highly more efficient transesterification catalyst than eGO.

2. RESULTS AND DISCUSSION 2.1. Carbon Black Oxidation. Graphite and CB samples used in the present study exhibit high surface areas (330 and 151 m2/g, respectively). The elemental analyses of high-surfacearea graphite and CB, after oxidation by the Hummers method15 or by the presently proposed method based on H2O2/H2SO4 (5/1 by volume), are compared in Table 1. As recently described,17 the Hummers oxidation method works well with both graphite and CB. The presently proposed method, based on H2O2/H2SO4, even when applied on highsurface-area graphite leads to a rather low oxidation degree (O/ C = 0.13), which is much lower than the one obtained by the oxidation of the same graphite by the Hummers method (O/C = 0.71). The proposed method is much more effective with high-surface-area CB and leads to an oxidation degree (O/C = 0.66), while is instead poorly effective on the CB samples of low surface area. For instance, the same procedure applied to a CB sample with SA = 36 m2/g provides an oCB sample with the O/C ratio close to 0.04. The elemental analysis results of Table 1 also indicate that both oxidation procedures leave the oCB sample with a high sulfur content, nearly double than that of graphite. It is worth adding that although the surface area of CB is noticeably reduced after oxidation by using the Hummers method, going down from 151 to 61 m2/g, the surface area of CB after oxidation with the H2O2/H2SO4 mixture is almost saved around 100 m2/g. Additional differences emerge from the comparison of infrared (IR) spectra of eGO and oCB (Figure 1). In particular, the oCB-1 sample presents well-defined peaks in the range 1300−900 cm−1 corresponding to the vibrations of ether, epoxy, alcoholic, and carboxylic groups which are much better defined than that for graphene oxide26 (Figure 2, oCB-1 vs eGO), as well as two peaks at 885 and 849 cm−1 assigned to the asymmetric stretching and deformation vibrations of epoxy groups, respectively, and a 575 cm−1 peak which could be possibly attributed to peroxides.26 Moreover, the well-defined peak at 1170 reveals the contribution of an increased amount of the sulfonic group.17 Also interesting is a comparison between Fourier transform infrared (FTIR) spectra of the oCB samples as oxidized by the

Figure 1. FTIR spectra in the range 2000−450 cm−1 of oxidized graphene (GO and eGO) and oCB, by the Hummers method (oCB1) or by the H2O2/H2SO4 mixture (oCB-2).

Figure 2. FTIR spectrum of oCB-2 before (a) and after (b) activation of transesterification reaction.

two different methods. As a matter of fact, although the two spectra were substantially superimposable and the 1170 cm−1 peak related to the presence of the sulfonic group is consistent for both the oCB samples as well, the carboxylic peak at 1718 cm−1 is much less intense for the CB sample oxidized by H2O2/ H2SO4 (oCB-2) than for the sample oxidized by the Hummers method (oCB-1) (Figure 2, oCB-1 vs oCB-2). 2.2. Transesterification Reactions. In a preliminary study, the ability of different nanocarbons to activate transesterification reactions was tested for ethyl 3-phenylpropanoate 1 and benzyl alcohol 2 under solvent-free conditions using a 7863

DOI: 10.1021/acsomega.7b01007 ACS Omega 2017, 2, 7862−7867

ACS Omega

Article

Table 2. Transesterification Reaction between Ethyl 3-Phenylpropanoate 1 and Benzyl Alcohol 2

entry 1 2 3 4 5 6 7 8 9b 10 11 a

catalyst (wt %)

T (°C)/t (h)

yield (%)a

HSAG (5) GO (5) GO (10) GO (5) GO (5) eGO (5) eGO (5) oCB-1 (5) oCB-2 (5)

60/24 80/24 80/48 60/24 60/24 80/24 80/48 80/48 80/48 80/18 80/18

19 30 35 57 53 70 75 85 64 92 99

All yields refer to the isolated products. bThe reaction was performed using 1/1 molar ratio of reagents 1 and 2.

molar ratio of 1:2 equiv for 1 and 2, respectively. The possible catalytic activity was explored by changing the loading and temperature conditions of nanocarbons (Table 2). As reported in Table 2, in the absence of a catalyst under solvent-free conditions, the reaction has a low yield (entry 1, Table 2) and even increasing the temperature to 80 °C, no significant improvement was detected (entry 2, Table 2). The yield remains low also in the presence of high-surface-area graphite (entry 3, Table 2), which has instead relevant catalytic activities for other reactions.10,27 The reaction, again under solvent-free conditions, is clearly activated by 5 wt % GO both at 60 °C and at 80 °C (entry 4 and 6, Table 2) with only a minor yield increase with a prolonged reaction time (entry 7, Table 2). It is worth adding that the increase of nanocarbon loading or the reduction of the amount of alcohol does not improve the yields (entry 5 and 9, Table 2). Significant increases of yields are instead obtained by replacing the crystalline GO with derived graphene oxide (eGO). In fact, as reported in Table 2 (entry 8), the use of GO after exfoliation by ball milling positively influence the reactivity by increasing the yield up to 85%. Additional relevant yield improvements are obtained by conducting the reaction in the presence of oCB-1, as oxidized by Hummers oxidation, providing the product 3a in 92% (entry 10, Table 2), and mainly in the presence of oCB-2 powder, as obtained from the new and mild oxidation procedure, providing the product in 99% yield in only 18 h (entry 11, Table 2). To evaluate the generality of the method, some reactions with different alcohols 2a−i and esters 1a−c at 80 °C were performed with some of the oxidized carbon materials under solvent-free conditions (Scheme 2). As reported in Table 3, although transesterification reaction proceeds quite well already in the presence of eGO (entries 1−

4, 7, and 8 of Table 3), a reduction of reaction time and higher yields are assured by the presence of oCB-1 and oCB-2. It has to be noted that although in the presence of aromatic esters the reaction catalyzed by eGO proceeds with a very poor (entries 4 and 8 of Table 3) and sometimes no yield (entries 5 and 6 of Table 3), the same reactions catalyzed by oCB-1 and oCB-2 proceed with moderate to excellent yields with sensible reduction of reaction time. The more efficient activation of the transesterification reactions is possibly due to the higher concentration on the oCB surface of the sulfonic groups, which are more acidic than carboxylic groups.28,29 It has to be noted that although the O/C ratio of oCB-2 is lower than that of oCB-1 (0.66 vs 0.83), the almost same sulfur content, about 6%, associated to a higher surface area of oCB-2 (100 m2/g) than the one reported for oCB-1 (61 m2/g), makes comparable the activity of two catalysts proposed. Therefore, to meet the growing need of more environmental and benign procedures, the use of catalyst oCB-2 obtained by the new mild and ecofriendly procedure has to be preferred. In this way, the reaction can be performed under solvent-free conditions and by using a completely metal-free catalyst obtained by a green procedure. It is worth adding that such a great efficiency in the presence of just 5 wt % oCB-2 heating the mixture at 80 °C under solvent-free conditions is a very intriguing result. In fact, the most reported procedures30,31 need to work for 16−24 h to provide similar results by using metals and in high catalyst loading, and similar efficiency has been previously reported just by using higher catalyst loading, at least 30 wt % sulfonated polypyrene, but in the presence of aromatic and aliphatic solvents as well as using necessarily higher temperature.31 Recently a sulfonated graphene oxide monolith was used for the esterification reaction giving good yields in 90 min but in the presence of catalyst loading close to 20 wt % and again in the presence of aromatic solvents.32 Finally, we investigated the recyclability of the recovered oCB-2 after the transesterification reaction between 3-phenylpropanoate 1 and benzyl alcohol 2. Recovered oCB-2 has a strongly reduced activation ability, with the yield reduced from 99% down to 45%, possibly because of a thermal desulfonation with consequent reduction of acidity. In fact, as reported in the IR spectrum of Figure 2, many vibrational peaks of oCB-2

Scheme 2. General Scope of the Reaction

7864

DOI: 10.1021/acsomega.7b01007 ACS Omega 2017, 2, 7862−7867

ACS Omega

Article

Table 3. Transesterification Reaction of Alcohol 2a−i with 1a−c Ester Catalyzed by eGO (5 wt %), oCB-1 (5 wt %) and oCB-2 (5 wt %)

a

All the yields refer to the isolated products.

3. CONCLUSIONS

disappear after the reaction (b vs a), indicating a decrease of concentration of the oxidized functional groups, mainly sulfonic groups, as also confirmed by the elemental analysis (sulfur content becoming less than 1.5 wt %). Interestingly, the recovered oCB-2 sample can be again oxidized under mild conditions by using the H2O2/H2SO4 5/1 mixture. The reoxidized oCB-2 sample can be reused for the activation of transesterification reactions, providing an efficiency very close to that of the first run (95% yield) (Figure 3). The activator is cheap and can be recovered and reoxidized by green and ecofriendly procedures.

A metal-free procedure for oxidation of CB, under mild and ecofriendly conditions, is described. The procedure, based on 5/1 w/w H2O2/H2SO4, leads, for high-surface-area CB, to an oxidation degree comparable to the one obtained with the more aggressive and metal-based Hummers method with the analogous sulfur content. This procedure is, however, poorly effective on low-surface-area CB as well as on graphite, even if exhibiting a very high surface area. 7865

DOI: 10.1021/acsomega.7b01007 ACS Omega 2017, 2, 7862−7867

ACS Omega

Article

Figure 3. oCB recovering and recycling.

(500 mg) was added into 500 mL of 30 wt % H2O2 in water under magnetic stirring. Then, H2SO4 was slowly dropped into the uniform dispersion. After 24 h, the mixture was diluted with 1.5 L of deionized water and then centrifuged at 10 000 rpm for 10 min with an Awel centrifuge. The isolated oCB powders were washed with 500 mL of deionized water. Finally, the powders were dried at 60 °C for 12 h. About 1.3 g of oCB (oCB-2) powders was obtained with a oxygen/carbon weight ratio of 0.66. 4.4. Exfoliation of GO by Ball Milling. The GO powders were introduced in a 125 mL ceramic jar (inner diameter of 75 mm) together with the stainless steel balls (10 mm in diameter) and were dry-milled in a planetary ball mill (Retsch GmbH 5657 Haan) for 2 h with a milling speed of 500 rpm and a ballto-powder mass ratio of 10:1. 4.5. Transesterification Reactions. The reactions were carried out in a flask. Details were given for the reaction of ethyl 3-phenylpropanoate (1 mmol, 178.2 mg, 176 μL) and benzyl alcohol (2 mmol, 216.3 mg, 208 mL). The reactants were added to the catalyst (5 wt % compared to the ester) at 80 °C. The reaction was stirred at the same temperature for the time indicated. The reaction mixture was extracted with ethylacetate (AcOEt), and the combined organic phase was dried (Na2SO4) and concentrated. The residue was purified by column chromatography (silica gel, petroleum ether/EtOAc, gradient) to obtain the pure product.

All considered oxidized nanocarbons are able to activate a broad scope of transesterification reactions under solvent-free conditions. Activation occurs already by graphene oxide, but it is much more pronounced by oCB, providing the product in reduced reaction times. The recovered oCB-2 can be again oxidized under mild conditions by using the H2O2/H2SO4 5/1 mixture. The reoxidized oCB-2 sample can be reused for the activation of transesterification reactions, providing an efficiency very close to that of the first run.

4. MATERIALS AND METHODS 4.1. Materials. High-surface-area graphite, with Synthetic Graphite 8427 as trademark, was purchased from Asbury Graphite Mills Inc., with a minimum carbon wt % of 99.8. The used CB samples, with surface area of 151 m2/g, were purchased from Cabot. All reagents were purchased from Sigma-Aldrich and used without any further purification. Thin-layer chromatography was performed on a silica gel 60 F254 0.25 mm glass plates Merck and nonflash chromatography was performed on a silica gel (0.063−0.200 mm) (Merck). All 1H NMR and 13C NMR spectra were recorded with a DRX 400 MHz instrument, by using CDCl3 (δ = 7.26 ppm in 1H NMR spectra and δ = 77.0 ppm in 13C NMR spectra) as a solvent (400.135 MHz for 1H and 100.03 MHz for 13C). For the products 3aa, 3ac, 3ae, and 3ad, the 1H NMR and 13 C NMR match with those reported in the literature.33−37 4.2. Oxidation of Graphite and CB with the Hummers Procedure. GO and oCB were prepared by the Hummers method.15 Sulfuric acid (120 mL) and sodium nitrate (2.5 g) were introduced into a 2000 mL three-neck round-bottomed flask immersed into an ice bath, and 5 g of carbon samples was added under magnetic stirring. After obtaining a uniform dispersion, 15 g of potassium permanganate was added very slowly to minimize the risk of explosion. The reaction mixture was thus heated to 35 °C and stirred for 24 h. Deionized water (700 mL) was added in small amounts into the resulting black and dark green slurry of CB and graphite, respectively, under stirring and, finally, gradually adding 5 mL of H2O2 (30 wt %). The obtained sample was poured into 7 L of deionized water and then centrifuged at 10 000 rpm for 15 min with a Hermle Z 323 K centrifuge. The isolated GO and oCB powders were first washed twice with 100 mL of a 5 wt % HCl aqueous solution and subsequently washed with 500 mL of deionized water. Finally, the powders were dried at 60 °C for 12 h. About 7.5 g of GO and 6.5 g of oCB powders were obtained. The obtained oxygen/carbon weight ratio is 0.71 for GO and 0.83 for oCB. 4.3. Oxidation of CB by H2O2/H2SO4. Oxidation of commercial CB was carried out in 5/1 H2O2/H2SO4. The CB



ASSOCIATED CONTENT

* Supporting Information S

The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acsomega.7b01007. Material and methods, synthetic procedures, characterization techniques, and 1H and 13C NMR spectra of the products (PDF)



AUTHOR INFORMATION

Corresponding Authors

*E-mail: [email protected]. Phone: +39089969392 (M.R.A.). *E-mail: [email protected]. Phone: +39089969558 (G.G.). ORCID

Maria Rosaria Acocella: 0000-0001-6917-2271 Gaetano Guerra: 0000-0003-1576-9384 Author Contributions

M.R.A. conceived and designed the experiments and participated in the interpretation of the results and the writing of the paper. C.A., N.A., and M.M. were responsible for the experiments and data analysis. G.G. supervised the research and participated in the interpretation of results and the writing 7866

DOI: 10.1021/acsomega.7b01007 ACS Omega 2017, 2, 7862−7867

ACS Omega

Article

(17) Maggio, M.; Acocella, M. R.; Guerra, G. Intercalation compounds of oxidized carbon black. RSC Adv. 2016, 6, 105565− 105572. (18) Pepels, M. P. F.; Bouyahyi, M.; Heise, A.; Duchateau, R. Kinetic Investigation on the Catalytic Ring-Opening (Co)Polymerization of (Macro)Lactones Using Aluminum Salen Catalysts. Macromolecules 2013, 46, 4324−4334. (19) Shi, H.; Zhang, H. Waste Oil and Fat Feedstocks for Biodiesel Production. Adv. Pet. Explor. Dev. 2014, 8, 31−36. (20) Vogelzang, E. J. W. J. Oil Colour Chem. Assoc. 1963, 4, 89−115. (21) Rehberg, C. E. Organic Synthesis; Wiley: New York, 1955; Collect. Vol. 3, pp 146−148 (22) Van Rhijn, W. M.; De Vos, D. E.; Sels, B. F.; Bossaert, W. D. Sulfonic acid functionalised ordered mesoporous materials as catalysts for condensation and esterification reactions. Chem. Commun. 1998, 317−318. (23) Harmer, M. A.; Farneth, W. E.; Sun, Q. Towards the sulfuric acid of solids. Adv. Mater. 1998, 10, 1255−1257. (24) Yadav, G. D.; Nair, J. J. Sulfated zirconia and its modified versions as promising catalysts for industrial processes. Microporous Mesoporous Mater. 1999, 33, 1−48. (25) Harmer, M. A.; Sun, Q.; Vega, A. J.; Farneth, W. E.; Heidekum, A.; Hoelderich, W. F. Nafion resin−silica nanocomposite solid acid catalysts. Microstructure−processing−property correlations. Green Chem. 2000, 2, 7−14. (26) Acik, M.; Lee, G.; Mattevi, C.; Pirkle, A.; Wallace, R. M.; Chhowalla, M.; Cho, K.; Chabal, Y. The Role of Oxygen during Thermal Reduction of Graphene Oxide Studied by Infrared Absorption Spectroscopy. J. Phys. Chem. C 2011, 115, 19761−19781. (27) Acocella, M. R.; D’Urso, L.; Maggio, M.; Guerra, G. Green Regio- and Enantioselective Aminolysis Catalyzed by Graphite and Graphene Oxide under Solvent-Free Conditions. ChemCatChem 2016, 8, 1915−1920. (28) Dhakshinamoorthy, A.; Alvaro, M.; Concepción, P.; Fornés, V.; Garcia, H. Graphene oxide as an acid catalyst for the room temperature ring opening of epoxides. Chem. Commun. 2012, 48, 5443−5445. (29) Dhakshinamoorthy, A.; Alvaro, M.; Puche, M.; Fornes, V.; Garcia, H. Graphene Oxide as Catalyst for the Acetalization of Aldehydes at Room Temperature. ChemCatchem 2012, 4, 2026−2030. (30) Xiang, J.; Toyoshima, S.; Orita, A.; Otera, J. A Practical and Green Chemical Process: Fluoroalkyldistannoxane-Catalyzed Biphasic Transesterification. Angew. Chem., Int. Ed. 2001, 40, 3670−3672. (31) Ohshima, T. Development of Tetranuclear Zinc ClusterCatalyzed Environmentally Friendly Reactions and Mechanistic Studies. Chem. Pharm. Bull. 2016, 64, 523−539. (32) Tanemura, K.; Suzuki, T. Sulfonated polypyrene (S-PPR) as efficient catalyst for esterification of carboxylic acids with equimolar amounts of alcohols without removing water. Tetrahedron Lett. 2013, 54, 1972−1975. (33) Nakhate, A. V.; Yadav, G. D. Synthesis and Characterization of Sulfonated Carbon-Based Graphene Oxide Monolith by Solvothermal Carbonization for Esterification and Unsymmetrical Ether Formation. ACS Sustainable Chem. Eng. 2016, 4, 1963−1973. (34) Black, P. J.; Cami-Kobeci, G.; Edwards, M. G.; Slatford, P. A.; Whittlesey, M. K.; Williams, J. M. J. Borrowing hydrogen: iridiumcatalysed reactions for the formation of C−C bonds from alcohols. Org. Biomol. Chem. 2006, 4, 116−125. (35) Kiyooka, S.-i.; Wada, Y.; Ueno, M.; Yokoyama, T.; Yokoyama, R. [IrCl(cod)]2-catalyzed direct oxidative esterification of aldehydes with alcohols. Tetrahedron 2007, 63, 12695−12701. (36) Maegawa, Y.; Ohshima, T.; Hayashi, Y.; Agura, K.; Iwasaki, T.; Mashima, K. Additive Effect of N-Heteroaromatics on Transesterification Catalyzed by Tetranuclear Zinc Cluster. ACS Catal. 2011, 1, 1178−1182. (37) Li, L.; Sheng, H.; Xu, F.; Shen, Q. Heterometal Clusters Ln2Na8(OCH2CH2NMe2)12(OH)2 as Homogeneous Catalysts for the Tishchenko Reaction. Chin. J. Chem. 2009, 27, 1127−1131.

of the paper. All the authors contributed to the realization of the manuscript and have given approval to the final version of the manuscript. Notes

The authors declare no competing financial interest.



ACKNOWLEDGMENTS We thank Prof. Pasquale Longo of the University of Salerno for useful discussions and Arianna Melillo for experimental support. Financial support of “Ministero dell’Istruzione, dell’Universita e della Ricerca” and Pirelli is gratefully acknowledged.

■ ■

ABBREVIATION GO, graphite oxide; eGO, exfoliated graphite oxide; CB, carbon black; oCB, oxidized carbon black REFERENCES

(1) Jia, H.-P.; Dreyer, D. R.; Bielawski, C. W. C−H oxidation using graphite oxide. Tetrahedron 2011, 67, 4431−4434. (2) Dreyer, D. R.; Jia, H.-P.; Bielawski, C. W. Graphene Oxide: A Convenient Carbocatalyst for Facilitating Oxidation and Hydration Reactions. Angew. Chem. Int. Ed. 2010, 49, 6686.10.1002/ anie.201003238; Angew. Chem. 2010, 122, 6965−6968.10.1002/ ange.201002160 (3) Boukhvalov, D. W.; Dreyer, D. R.; Bielawski, C. W.; Son, Y.-W. A Computational Investigation of the Catalytic Properties of Graphene Oxide: Exploring Mechanisms by using DFT Methods. ChemCatChem 2012, 4, 1844−1849. (4) Jia, H.-P.; Dreyer, D. R.; Bielawski, C. W. Graphite Oxide as an Auto-Tandem Oxidation−Hydration−Aldol Coupling Catalyst. Adv. Synth. Catal. 2011, 353, 528−532. (5) Navalon, S.; Dhakshinamoorthy, A.; Alvaro, M.; Garcia, H. Carbocatalysis by Graphene-Based Materials. Chem. Rev. 2014, 114, 6179−6212. (6) Navalon, S.; Dhakshinamoorthy, A.; Alvaro, M.; Antonietti, M.; García, H. Active sites on graphene-based materials as metal-free catalysts. Chem. Soc. Rev. 2017, 46, 4501−4529. (7) Acocella, M. R.; Mauro, M.; Guerra, G. Regio- and Enantioselective Friedel−Crafts Reactions of Indoles to Epoxides Catalyzed by Graphene Oxide: A Green Approach. ChemSusChem 2014, 7, 3279−3283. (8) Kumar, A. V.; Rao, K. R. Recyclable graphite oxide catalyzed Friedel−Crafts addition of indoles to α,β-unsaturated ketones. Tetrahedron Lett. 2011, 52, 5188−5191. (9) Verma, S.; Mungse, H. P.; Kumar, N.; Choudhary, S.; Jain, S. L.; Sain, B.; Khatri, O. P. Graphene oxide: an efficient and reusable carbocatalyst for aza-Michael addition of amines to activated alkenes. Chem. Commun. 2011, 47, 12673−12675. (10) Acocella, M. R.; Mauro, M.; Falivene, L.; Cavallo, L.; Guerra, G. Inverting the Diastereoselectivity of the Mukaiyama−Michael Addition with Graphite-Based Catalysts. ACS Catal. 2014, 4, 492−496. (11) Acocella, M. R.; De Pascale, M.; Maggio, M.; Guerra, G. Graphite oxide as catalyst for diastereoselective Mukaiyama aldol reaction of 2-(trimethylsilyloxy)furan in solvent free conditions. J. Mol. Catal. A: Chem. 2015, 408, 237−241. (12) Mirza-Aghayan, M.; Boukherroub, R.; Rahimifard, M. Graphite oxide as an efficient solid reagent for esterification reactions. Turk. J. Chem. 2014, 38, 859−864. (13) Brodie, B. C. On the atomic weight of graphite. Philos. Trans. R. Soc. London 1859, 149, 249−259. (14) Staudenmaier, L. Verfahren zur darstellung der graphitsäure. Ber. Dtsch. Chem. Ges. 1898, 31, 1481−1487. (15) Hummers, W. S.; Offeman, R. E. Preparation of graphitic oxide. J. Am. Chem. Soc. 1958, 80, 1339. (16) Dicks, A. L. The role of carbon in fuel cells. J. Power Sources 2006, 156, 128−141. 7867

DOI: 10.1021/acsomega.7b01007 ACS Omega 2017, 2, 7862−7867