MEETINGS
HPCE '92 The 4th International Symposium on High-Performance Capillary Electrophoresis will be held Feb. 9 - 1 3 , 1992, at the RAI Congress Centre in Amsterdam, The Netherlands. The scientific program includes 45 oral presentations and more t h a n 100 posters as well as an instrumentation exhibit. Sessions will address the principles of separation in capillaries under high electrical fields, the latest in instrumentation development, and applications of HPCE, particularly in analytical biotechnology. In addition to the traditional oral and poster presentations, topical discussion sessions will be held on Tuesday and Thursday afternoon. An exhibit of capillary electrophoresis systems as well as components, materials, and reagents used in HPCE and other s e p a r a t i o n s techniques will take place on Tuesday, Wednesday, and Thursday. For further information, contact Shirley E. Schlessinger, Symposium Manager, HPCE '92, 400 East Randolph St., Suite 1015, Chicago, IL 60601 (312-527-2011). The technical program follows.
Program
8:45 9:15
9:40
4:20
4:40
5:00 Session 2. Recent Advances in Instrumentation 10:45 Evaluation of an HPCE Apparatus Designed According to New Principles. S. Hjerten, T. Srichaiyo, and A. Palm, University of Uppsala, Sweden 11:10 Planar Chips Technology for Electrophoretic Systems. A. Manz and Η. Μ. Widmer, Ciba-Geigy, Switzerland; and D. J. Harrison, University of Alberta, Canada 11:30 Ultrasensitive Fluorescence Detector for CE. J. M. Ramsey and W. B. Witten, Oak Ridge National Laboratory; S. Arnold, Polytechnic University of New York; and K. C. Ng, California State University, Fresno 11:50 Optimization of a Colinear Laser-Induced Fluorescence Detector for CE. L. Hernandez, E. Murzil, and N. Joshi, Los Andes University, Venezuela; P. Verdeguer, Europhor, France; and N. A. Guzman, Hoffman-La Roche
Poster Session 1. Applications (1:30-3:30) Session 3. DNA Sequencing 3:30
MONDAY 3:55 Session 1 . HPCE: General 8:30 Opening of symposium. F. M. Everaerts, Eindhoven University of Technology, The Netherlands
Keynote lecture: Present and Future Role of CE in Biomedicine. E. Jellum, University of Oslo, Norway Discrimination between Similar Protein Species by CE. F. E. Régnier, J. Κ. Towns, Β. Harmon, and X. W. Yao, Purdue University Capillary Isotachophoresis: A Technique for On-Line Sample Preparation in CZE. D. Kaniansky and J. Marak, Comenius University, Czechoslovakia
Capillary Gel Electrophoresis for DNA Sequencing. N. J. Dovichi, D. Chen, H. R. Harke, M-J. Rocheleau, J. J. Zhang, S. J. Bay, and R. J. Grey, University of Alberta Multiwavelength Fluorescence Detection for Capillary DNA Sequencing. A. E. Karger, J. M. Harris, and R. F. Gesteland, University of Utah
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High-Resolution Polyacrylamide Capillary Gel Electrophoresis with Laser-Induced Fluorescence Detection for DNA Sequencing. A. S. Cohen, S. Carson, A. Belinkii, and B. L. Karger, Northeastern University Recent Developments in DNA Sequencing by CE. H. Drossman, J. A. Luckey, A. J. Kostichka, and L. M. Smith, University of Wisconsin; and A. P. Land, D. H. Smith, and T. Brennan, Genomyx Single-Fluor Approach to DNA Sequence Determination Using Laser-Induced Fluorescence and Capillary Gel Electrophoresis. S. L. Pentoney, Jr., and K. D. Konrad, Beckman Instruments
TUESDAY Session 4. CE/MS 8:30
8:55
9:20
9:45
Microelectrospray: Characterization of Electrosprays at Nanoliter-per-Second Flow Rates. D. M. Dohmeier, T. L. Austell, and J. W. Jorgenson, University of North Carolina at Chapel Hill Instrumental Aspects of CZE/MS. Κ. Β. Tomer, L. J. Deterding, C. E. Parker, and J. R. Perkins, National Institute of Environmental Health Sciences Analyte Focusing in CE Using On-Line Isotachophoresis and Its Potential for Low Flow-Rate MS Interfaces. U. Tjaden, D. Stegehuis, N. Reinhoud, E. Verheij, and J. van der Greef, University of Leiden, The Netherlands On-Line Coupling of LC and CE with Tandem MS for Fast Structure Elucidation of Components from Complex Mixtures. E. Bauer and D. Waidlich, University of Tubingen, Germany
Session 5. Micelle Formers and Other Buffer Additives 10:30 Extension of Electrokinetic Chromatography: Use of Polymers, Emulsion, Latexes, and Inorganic Fine Particles. S. Terabe, Hemeji Institute of Technology, Japan; and N. Matsubaral and Y. Ishihama, Kyoto University, Japan
MEETINGS 10:55
11:20
11:45
12:05
Micelles with Adjustable Surface Charge Density for MECC. Z. El Rassi, J. Cai, and D. Cheadle, Oklahoma State University Analogy between Micelles and Polymers of Ionic Surfactant: A Capillary Isotachophoresis Study of Small Ionic Aggregates in Hydro-Organic Solutions. C. Tribet and R. Gaboriaud, Université Pierre et Marie Curie, France; and P. Gareil, ESPCI, France Use of Antibiotic Vancomycin as a Chiral Selector in CE. J. L. Carpenter and D. M. Goodall, University of York, U.K.; and P. Camilleri and G. N. Okafo, SmithKline Beecham, U.K. Chiral Separations by CE Using Cyclodextrin Derivatives. I. Cruzado, Y. Rawjee, and G. Vigh, Texas A&M University
Poster Session 2. Theory and Instrumentation (1:30-3:30) Session 6. Surface Coatings and Gels 3:30 Contributions to the Chemistry of Surface Coatings and Gels with Polyacrylamides and Agarose in CE. G. Schomburg, M-H. Kleemiss, J. A. Lux, A. R. Motsch, and H-F. Yin, Max-Planck-lnstitut fur Kohlenforschung, Germany 3:55 Chemical or Dynamic Coating of Capillary Surfaces in CE. H. Engelhardt, W. Beck, and J. Kohr, Universitât des Saarlandes, Germany 4:20 Bonded Columns versus GC Phases: A Comparison of Effectiveness for Use in CE. A. M. Dougherty, J. D. McCulloch, C. T. Silverstein, and C. L. Woolley, Supelco 4:40 Protein-Based Capillary Gel Electrophoresis for the Separation of Optical Isomers. S. Nilsson and S. Birnbaum, University of Lund, Sweden
Discussion Session 1. Advances in HPCE Instrumentation (5:00-6:00) WEDNESDAY Session 7. Innovations in Sieving CE 8:30
8:55
9:20
9:40
Optimization of Biopolymer Separations Using Polymer Networks. B. L. Karger, A. S. Cohen, D. Smisek, K. Ganzler, and A. Belinkii, Northeastern University Potentialities of the Solutions of Agarose for CZE Separations Based on Molecular Sieving. P. Bocek and A. Chrambach, National Institutes of Health Theoretical and Experimental Analysis of DNA Sequencing Electrophoresis. P. D. Grossman, S. Menchen, and D. Hershey, Applied Biosystems Capillary Affinity Gel Electrophoresis of Biologically Important Molecules. A. Guttman and N. Cooke, Beckman Instruments
Session 8. New Approaches in CE Separations 10:30
10:55
11:20 11:45
CE in Complex Matrices: Preconcentration of the Sample or Amplification of a Specific Solute? F. M. Everaerts, Eindhoven University of Technology, The Netherlands How Well Can We Predict Electrophoretic Separations? H. Poppe and G. J. Bruin, University of Amsterdam, The Netherlands Approaches Toward Gradient Elution in CE. Ε. S. Yeung, lowa State University Thermal Gradient MECC. R. Weinberger, Spectra-Physics Analytical
12:05
Thermal Degradation of a Thermolabile Serratia marcescens Nuclease Using CE under Stacking Conditions. A. Vlnther, Novo Nordisk, Denmark; and H. Sôeberg, L. Nielsen, J. Pedersen, and K. Biedermann, The Technical University of Denmark
THURSDAY Session 9. Analysis of Proteins and Peptides I 8:30 8:55
9:15 9:35
CE Peptide Mapping at High Sensitivity. M. Novotny, K. Cobb, D. Rice, and O. Shirota, Indiana University Fluorescence CE: Profiling Trace Chemical Degradation. R. W. Giese, W. Li, and A. Moussa, Northeastern University CE of Hemoglobin and Globin Chains. M. Zhu, R. Rodriguez, and T. Wehr, Bio-Rad Laboratories Analysis of Serum Proteins by CE. O. W. Reif, Κ. Hebenbrock, and Κ. Schugerl, Universitât Hannover, Germany
Session 10. Analysis of Proteins and Peptides II 10:25
10:50
11:10 11:30
Two-Dimensional Mapping of Oligosaccharides in Glycoproteins by HPCE. S. Honda, S. Suzuki, A. Nitta, and K. Kakehi, Kinki University, Japan Separation and Analysis of the Glycoform Populations of Ribonuclease Β Using CE. P. M. Rudd, E. Coghill, and R. A. Dwek, University of Oxford, U.K. Electrophoretic Characterization of Interferon-Y. M. J. Field, R. G. Keck, and J. V. O'Connor, Genentech CE for Monitoring Deblocking and Assembly of Bioactive Peptides. T. E. Wheat, J. D. Dixon, D. W. Andrews, and G. Vella, Waters Division of Millipore
Discussion Session 2. CE in Analytical Biotechnology (1:00-2:00) Session 1 1 . Bioanalytical Applications 2:00 Effect of Direct Control of Electroosmosis on Separation Efficiency and Resolution in CE. C. S. Lee, P. Tsai, C-T. Wu, and B. Patel, University of Maryland—Balti more County 2:20 Analysis of Natural and Synthetic Heparin Fragments by HPCE. J.B.L. Damm, G. T. Overklift, V. Kleyn, M.H.J.M. Langenhuizen, and P.S.L. Janssen, Akzo Pharma Division, Organon Int., The Netherlands 2:40 Determination of Pentamidine and Its Analogs and Metabolites by CE. L. E. Henry, B. J. Berger, J. E. Hall, and R. E. Tidwell, Dionex and University of North Carolina at Chapel Hill 3:00 Analysis of Fermentation Parameters by CE. Κ. Hebenbrock and K. Schugerl, Universitât Hannover, Germany 3:20 Keynote Lecture: High-Speed DNA Sequencing in Ultrathin Gels. L. M. Smith, R. L. Brumley, E. Buxton, H. Drossman, A. J. Kostichka, J. Luckey, and D. Mead, University of Wisconsin 3:50 Closing remarks.
Conferences • 1992 W i n t e r C o n f e r e n c e o n Plasma Spectrochemistry. Jan. 6 - 1 1 . S a n Diego, CA. Contact: R. Barnes, Dept. of Chemistry, GRC Towers,
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University of Massachusetts, Amherst, MA 01003-0035 (413-545-2294; fax 413-545-4490) • Winter Conference on F l o w Injection Analysis. Jan. 12-15. Scottsdale, AZ. Contact: WCFIA, Gary D. Christian, Dept. of Chemistry BG-10, University of Washington, Seattle, WA 98195 (206-543-1635; fax 206-6853478) • Winter Gordon R e s e a r c h Conference o n Composites. Jan. 1 3 17. Ventura, CA. Contact: Alexander Cruickshank, Gordon Research Conferences, Gordon Research Center, University of Rhode Island, Kingston, RI02881 (401-783-4011 or-3371) • Fullerene Molecules: Scientific and Technological Opportunities. J a n . 1 8 - 2 3 . Tucson, AZ. Contact: Charles Freiman, Engineering Foundation, 345 East 47th St., New York, NY 10017 (212- 705- 7835) • Winter Gordon R e s e a r c h Conf e r e n c e o n Electrochemistry. Jan. 2 0 - 2 4 . Ventura, CA. Contact: Alexander Cruickshank, Gordon Research Conferences, Gordon Research Center, University of Rhode Island, Kingston, RI 02881 (401-783-4011 or-3371) • Winter Gordon R e s e a r c h Conference on N o n d e s t r u c t i v e Evalu a t i o n . Jan. 2 0 - 2 4 . Oxnard, CA. Contact: Alexander Cruickshank, Gordon Research Conferences, Gordon Research Center, University of Rhode Island, Kingston, RI 02881 (401-783-4011 or-3371) • Sanibel Conference on Lasers i n Mass Spectrometry. J a n . 2 5 - 2 8 . Sanibel Island, FL. Contact: Judith A. Watson, ASMS, P. O. Box 1508, East Lansing, MI 48826 (517-337-2458) • Superfund Risk A s s e s s m e n t i n Soil C o n t a m i n a t i o n Studies. Jan. 3 0 - 3 1 . New Orleans, LA. Contact: Keith Hoddinott, U.S. Army Environmental Hygiene Agency, Attn: HSHB-ME-SE, Aberdeen Proving Ground, MD 210105422 (301-671-2953) • 4th International Symposium o n H i g h - P e r f o r m a n c e Capillary E l e c t r o p h o r e s i s . Feb. 9 - 1 3 . Amsterdam, The Netherlands. Contact: Shirley Schlessinger, HPCE '92, 400 East Randolph St., Suite 1015, Chicago, IL 60601 (312-527-2011) • Winter Gordon R e s e a r c h Conference o n the Chemistry and Bi o l o g y of P e p t i d e s . Feb. 1 0 - 1 4 . V e n t u r a , CA. Contact: Alexander Cruickshank, Gordon Research Conferences, Gordon Research Center, University of Rhode Island, Kingston, RI 02881 (401-783-4011 or-3371) • A m e r i c a n A c a d e m y of F o r e n sic S c i e n c e s 44th A n n u a l Meeting. Feb. 17-22. New Orleans, LA. Contact: Anne Warren, AAFS, P.O. Box 669, Colorado Springs, CO 80901-0669
