Potential antidiabetics. 11. Preparation of 4-arylazo-3,5-disubstituted

Chem. , 1972, 15 (4), pp 435–436. DOI: 10.1021/jm00274a035. Publication Date: April 1972. ACS Legacy Archive. Cite this:J. Med. Chem. 15, 4, 435-436...
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Journal of Medicinal Chemistry, I972, Vol. 15,No.4

Notes

Potential Antidiabetics, 11. Preparation of 4-Arylazo-3,5-disubstitu ted-(W)-l12,6-thiadiazine 1,l-Dioxides

435

Table I. CArylazo-3,5-dimethyl/diphenyl-(2H>1,2,6-thiadiazine 1,l-Dioxides NI

H. G . Garg* and Chandra Prakash

=

N

~

X

RCYC*CR

Department of Chemistry, Universify of Roorkee, Roorkee, India. Received October 11, 1971 0 2

The synthesis and evaluation of pyrazoles which are potent inhibitors of the release of free acids from tissue, causing a hypoglycemic effect,ly2have been previously reported from this laboratory.' Urea derivatives comprising the structural elements, >NS02NHC=C