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reactive ocetyiemc alcohols and naiides PROPARGYL
ALCOHOL reactions
HC=CCH2OH
Oxidation —^Propiolaldehyde HC==CCH0 Oxidative Coupling—^2,4-Hexadiyne-l,6-dioI H0CH2C=C--C=CCH20H Replacement of OH—*.Propargyl halides HC=CCH2X Halogenation—>>3-Halo-2-propyn-l-ol CIC=CCH20H Also reduction, esterification, hydration, trimerization, etc.
Three centers of reactivity —primary alcohol —active hydrogen—triple bond
suggested PROPARGYL
applications
BROMIDE
Chemical intermediate for Sulfadiazine and other pharmaceuticals, for agricultural chemicals, textile auxiliaries, etc. Corrosion inhibitor and stabilizer for halogenated compounds.
CHLORIDE
reactions
HC=CCH,Br PROPARGYL HC=CCH,CI
Reformatsky type-
CHa •Acetylenic carbinols Η0=0ΟΗ20-ΟΗ=ΟΗ2 OH
Three centers of reactivity—active halide—active hydrogen—triple bond
Amination—^Propargyl amines HC=CCH2NHR Etherification—^Propargyl ethers HC==CCH20R
suggested
applications
Chemical intermediates for terpenes and pharmaceuticals including vitamins, hormones, etc. Agricultural uses as soil fumigants, etc.
2-BUTYNE-1.4-DIOL HOCH,C=CCH,OH
reactions Replacement of OH—^l,4-Dihalo-2-butyne XCH2C=CCH2X Isomerization-—^Hydroxymethyl vinyl ketone H0CH2COCH=CH2 Trimerization—^HexamethylolbenzeneC6(CH2OH)6 Alcohol Addition—^Alkyl ether of 1,4 dihydroxy-2-butanone H0CH2C0CH2CH20R Also hydrogénation, esterification, halogenation, hydration, etherification, etc.
Reacts as a glycol and a disubstituted acetylene
suggested
applications
Chemical intermediate for pharmaceuticals, solvents, explosives, plasticizers, plastics, etc. Corrosion inhibitor and stabilizer for halogenated compounds.
GENERAL ANILINE & FILM CORPORATION
£
COMMERCIAL DEVELOPMENT DEPARTMENT Ν EW Y O R K 1 4 Ν. Υ H U DSON
