Anal. Chem. 2009, 81, 7856–7857
Response to Correspondence on “Linear and Branched Perfluorooctane Sulfonate Isomers in Technical Product and Environmental Samples by In-Port Derivatization-Gas Chromatography-Mass Spectrometry” Rayne and Forest1 made several comments on our recently published paper where we report on a novel analytical method for the separation of linear and branched chain isomers of perfluorooctane sulfonate (PFOS) in a technical product and in several representative liver, plasma, or egg samples of mammals and birds.2 Criticism was expressed on our statement that on the basis of various configurations of the C8 hydrocarbon chain that hundreds of PFOS isomers are theoretically possible. We agree with Rayne and Forest that we were not entirely clear and that when all possible geometrical and optical isomers are considered that there are
