Synthesis of 1-Epicyclocolorenone and Stereochemistry of

Dan Stærk, Brian Skole, Flemming S. Jørgensen, Bogdan A. Budnik, Patrick Ekpe, and Jerzy W. Jaroszewski. Journal of Natural Products 2004 67 (5), 79...
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3403 C, 65.7; H,9.4; N, 8.7. When the same reaction was run keeping the temperature of the stirred mixture at 35-40" for 40 hr and 50" for 5 hr, 95% of the silane was consumed and the yields were: 35% of XI, 40z of XIV, 20 of XIII, and 5 % of XII, based on Cpicoline reacted. Silylation of 2-Picoline. When trimethylsilane was passed into a stirred suspension of Pd catalyst (10% on carbon) in dry 2-picoline in the same manner used for the other picolines, no reaction was observed. A faint trace (