Organic Process Research & Development 2008, 12, 940–945
The Swern Oxidation: Development of a High-Temperature Semicontinuous Process J. Russell McConnell,* James E. Hitt, Edward D. Daugs, and Troy A. Rey The Dow Chemical Company, Midland, Michigan 48674, U.S.A.
Abstract: The Swern oxidation has been widely exploited for the oxidation of alcohols to their respective carbonyl compounds. The cryogenic operating conditions (