Only Waters this much advanced Breakthrough in automated derivatization technology.
Microbore for both isocratic and gradient analyses. Column: Waters Microbore M BONDAPAK'" Phenyl 2mm χ 30cm
50 picomoles each component 1. Aspartic Acid 2. Glutamic Acid 3. Asparagine 4. Serine 5. Glutamine 6. Histidine 7. Glycine 8. Threonine 9. Arginine 10. Alanine 11.Ï Amino Butyric Acid 12. Tyrosine 13. Methionine 14. Valine 15. Phenylalanine 16. Isoleucine 17. Leucine 18. Lysine
Column: Waters μBONDAPAK Phenyl 3.9mm χ 30cm
1. Hydrocortisone 2. Cortisone 3. Corticosterone 4. Hydrocortisone acetate 5. Cortisone acetate Inject
27 min.
High-speed pre-column derivatization and analysis of primary amino acids with unparalleled sensitivity. Waters eliminates the need for manual pre-column derivative formation by automating metering, mixing, timing the reaction, injecting and separating derivatized samples. This breakthrough technology gives you all the reproducibility and ease of automation plus high-speed, high-resolution chromatography. Ask for Bulletin #101. High-speed HPLC with high resolution.
Inject
This microbore separation of steroids shows a four fold increase in sensitivity with a Waters system. Waters systems give you microbore sensitivity for your sample limited applications. And you have the versatility to switch to any analytical to milligram scale prep application without system modification. Ask for Bulletin #102.
Extended capabilities in compound isolation and purification.
Column: Waters Z-Module™ Radial Compression Separation System with Radial-PAK 5 μ C 18 cartridge
Aromatics
Polars
Saturates 1. Methylparaben 2. Ethylparaben 3. Propylparaben 4. Butylparaben RI UV Inject
66 sec.
A 66-second separation of parabens with a Waters system. Combining advanced systems design with innovative radial compression column technology allows you to achieve high-speed HPLC without sacrificing resolution. Ask for Bulletin #103.
Inject
23 min.
Preparative separation of crude oil to fractionate saturates, aromatics and polars. Waters systems with new solvent delivery capabilityflow rates from 10 microliters to 45 milliliters per minutecombined with a wider range of columns give you expanded preparative capabilities. Ask for Bulletin #107.
systems offer HPLC capability: Multi-dimensional HPLC.
Automatic Peak Identification.
Sample spiked with standard
A acetate Ε succinate D2 Ε acetate A palmitate
Column: LRadial-PAK" SAX cartridge 2. Radial-PAK C, cartridge
1. Uracil 2. Cytidine, & Uridine 3. Thymidine 4. Adenosine
J»J Inject
18 min.
Automatic sample spiking with vitamin A acetate to verify retention time and elution order. Waters systems let you verify the identity of peaks of interest by determining the true elution order and retention times of corresponding standards within the sample matrix. This new, fully automated technique is based on the automatic addition of standards into the sample matrix prior to analysis. Ask for Bulletin #105.
45 min.
Inject
Fully automated high resolution separation of nucleotides, nucleosides and bases in a single chroma tographic analysis. Unique Waters systems capability utilizes different column selectivities—ion exchange and reverse p h a s e to separate highly complex samples with widely varying characteristics in a single run. Ask for Bulletin #104.
GPC and LC Data Reduction.
Push the limits of your chromatography further than ever before with a Waters HPLC system. These are just a few examples of how Waters systems combine sophisticated instrumen tation with innovative chemistry to bring you advanced HPLC capabilities. And we back that up with the best application support, service and training in the industry. Call or write today. We'll prove it. Inject
Determination of molecular weight distribution of the polymer (GPC) and quantitative determination of the additives by weight-percent (LC) in a single analysis. This unique Waters systems capability gives you both GPC and LC data reduction in a single analysis for the most complete information about your sample. Ask for Bulletin #106.
Waters
Waters, the Liquid Chromatography People®
MILLIPORE
34 Maple St/Milfcxd, MA 01757/(617)478-2000 CIRCLE 235 ON READER SERVICE CARD
Looking at automated AA? You probably need an IL Plasma·
You may already know that you'd prefer an ICP, but you think you can't afford it. Look again. With compar able data readout, an IL Plasma is similar in price, and it gives you vast advantages. • Really easy to use. In routine operation, the ten function keys (above) control the entire instrument. • No lamps to align. Noburnerto adjust. • As many elements as you want in one analysis. • Very high linear range. No multiple standards required. No successive sample dilutions. • Detection limits are much better for refractories. B, P, Ti, U, W, and Zr are easy. • All data for a given sample appear at once. No waiting until all the samples are run. • NEW! The PHD™ (Plasma Hydride Device) permits the determination of hydrides and non-hydrides simultaneously in the same sample. • NEW! Even higher analytical speed. Uptoa rate of 18elements/min. in single-channel, 24elements/min. in the exclusive two-channel model. • NEW! The Semiquant™ program, which quickly gives approximate results for any sample, with no need for special standards. • FREE ! A reprint, "AA or ICP?" which compares the techniques fairly, clearly, authoritatively.
New Products
Model 346 CL Corrosive Liquid Submicron Sensor is a laser-based particle counter for sizing and counting particles in any liquid that will not affect KEL-F or sapphire. Features include 0.5-μιτι sensitivity, sample flow rate of 100 mL/min, large sample passageway to prevent clogging, and compatability with corrosive chemicals and solvents. Pacific Scientific 402
HPLC Pump Model 303 is designed to meet higher operating pressures and delivers largescale preparative flow rates against high system back pressures. The pump uses several pumping heads to deliver flow-rate ranges of 5 μ ι to 5 mL/min at 10 000 psi; 10 μL to 10 mL/min at 10 000 psi; 50 μL· to 50 mL/min at 2000 psi; and 100 μί. to 100 mL/min at 1000 psi. Gilson Medical Electronics
413
Amino Acid Analysis Model 3A29 Analyzer runs 40 samples without operator intervention, complet ing hydrolyzed protein analysis in 1 h and physiological fluid sampling in < 3 h. It provides three-channel signal monitoring—440 nm, 570 nm, and 690 nm (reference). Safety features include an overflow monitor to prevent spillage and an interlock device to prevent sam pler jamming. Erba Instruments 419
Gas Chromatographic Infrared Analyzer CIRA 102 is a GC integrated with an in frared cell and designed to mount into the sample compartment of any IR spectrometer. The CIRA contains a valving system by which peaks eluting off the GC can be trapped in the IR cell for infrared analysis. The instrument's stop-flow operation is achieved with lit tle or no consequential diffusion or loss of resolution of subsequent eluting peaks. Sadtler Research Labs 418
Small Helium-Neon Lasers Two small lasers for OEM applications will be of interest to manufacturers who need reduced envelope size and weight while retaining reliability and long, sta ble life. The smaller one is rated at 0.5 mW (mean delivered output power is 1.2 mW). The second laser is rated at 1.0 mW (mean delivered power is 1.8 mW). Melles Griot 421
Instrumentation Laboratory Inc. 56 Jonspin Road, Wilmington, MA 01887 In the final analysis...
Instrumentation Laboratory
Radiation-Heated DTA System uses a halogen lamp as a heat source. Heating rates up to 100 °C/min are easily achieved with excellent baseline stability. The furnace is controlled and programmed via a microprocessor. Samples are placed in small quartz ampules, with ther mocouples in direct contact with the sample and reference. Netzsch 405
CIRCLE 108 ON READER SERVICE CARD
1496 A · ANALYTICAL CHEMISTRY, VOL. 54, NO. 14, DECEMBER 1982
