Zinc Sulphinates - Diversification with ease - C&EN Global Enterprise

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Zinc Sulphinates – Diversification with Ease DFMS L510084

TFMS L510106

IPS L511161

TFES L511234

The Baran Group has teamed up with Aldrich Chemistry to provide a toolkit of reagents which are:

• Bench-stable, free-flowing solids • Highly efficient under open-flask conditions • Compatible with unprotected late-stage intermediates • Enable selective one-pot sequential alkylations These products allow for easy diversification of heterocycles found in the recent Nature paper “Practical and Innate Carbon-Hydrogen Functionalization of Heterocycles.”

Toolkit for Easy Diversification

Innate C-H Functionalization TFMS then IPS (one pot)

To find out more about the products available from Aldrich Chemistry and the Baran Laboratory, visit

Aldrich.com/baranreagents

References: Fujiwara, Y.; Dixon, J. A.; O’Hara, F.; Funder, E. D.; Dixon, D. D.; Rodriguez, R. A.; Baxter, R. D.; Herle, B.; Sach, N.; Collins, M. R.; Ishihara, Y.; Baran, P. S. Nature 2012, 492, 95-100.

©2013 Sigma-Aldrich Co. LLC. All rights reserved. SIGMA-ALDRICH and ALDRICH are trademarks of Sigma-Aldrich Co. LLC, registered in the US and other countries. ADD ALDRICH is a trademark of Sigma-Aldrich Co. LLC.

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