book reviews
results are well correlated and rhe interpretnriun and sprculatim ore more ex1emir.e l h m one can write in a research pdprr lor journal publication, 1) Approaches to Csrhoxyl-Tcrmmal Sequencing and End-Gmup Determinations in Peptidm G. Marc Unfortunately, for the majority of stuLaudon. M. E. Psrhsm, MswinJ. Miller dents, teachers, and even researchers, this is 5 ) ~~t~~~~tionsofSel~~todAntitumorAntibioticswith not a set of volumes far individual purchase. Nvcleic Acids, J. W. LoThe ~ u r c h a s eorice is orohibitive. However. 6) CompoaitionandStmetvreofThermalCandemtion Polymerr of Amino Acids. Paul Meliua 7) The Riwreanic Chemistry of Aggregatd Molecules,
F.M. Menger 8) Recent Studieson BioadiveCampounds. Kaii Nak-
William S. Mungall
Hope College Holland Michigan 49423
Robins 12) Chemical Reanions of Nucleie Acids, Rohart Shs-
piro 13) B i ~ o q a n i e Stereothemistry: Unuaual Structures. ClsvdioTnniolo
Peptide
Volume IV: Electron Tmnsfer and Ener~Conver8ion:Coisctora: Probps 11 Photosynthetic Phorphorylation: Conversion of Sunlight into Biochemical Energy, Daniel J. Arnon 2) Oxidation end oxygen Activation by Heme Protein.. C. K. Changand D. Dolphin 31 Affinity Labeling Studies on E~cherichiocoli Ribosomes. Barry S. cooperman 1) Mechanisms of Elmtrnn Transfer by High Potential e-TypeCytochromes. MichselA.Cusanovich 51 Structural and Mechanistic Aspects of Catalysis by Thiamin, Anthony A. Gallo, John J. Mieyal, and Henry 2. Sable 61 Cytokinin Antagonists: Regulationof the Growthof Plant and Animsl Cells, Sidney M. Hecht 7) Speeiiie Chemical Pcobesfot Elucidatiog the Meehanism of Steroid Hormone Action: P~OKIOPP U~ing Estrogen Photoaffinity Labeling Agents, John A. Kaf~enellenho~en, Howard J. Johnson, Jr.. Harvey N. Myers, Kathryn E. Carlson, and Robert J. Kempton 8) Tho Redox Chemistry of 1.4-Dihydronieotinic Acid Dociuatiues.D. A. Widdowson and R. J. Kill s) Mod& for the Role of Magnesium Lon in Enzymatic Catalysis. P h m ~ k t e T r a n s f e rand , Enolate Farmati"", Ronald ~ i u g e r 10) Some Prnblemr in Biophysicsl 01ganic Chemistry. Edwara M. K m w e r 11) Photoredox Readionad Porphyrins and the Origins of Phutvbyntheria, D. Mauzerall 121 Mechanisms of Enzymelike Reactions Involving Human Hemoglobin, John J. Mieyal 13) Intoractinns of Transition-Metal Ions with Amino ~ c i d sOlkopeptider, , and RelatedCompounds, Akitsueu Nakahara. Osamu Yamauchi. and Yaauo ~niao 14) NonenzymsticDihydmnicotinamideRedudionsas Proka for the Mechanism of NADt-Dependent Dehydrogenases, David S. Sigmnn, .Joseph Hajdu. and Donald .J. Creighton 1s) The Use of Puromyein Analoga and Related Compounds to Probe the Active center of Peptidy1 Tranrferase on Escherichia coli Ribmamea, Robert H . Symons, Raymond J. Harris, Philip Greenwell. David J. Frkermann, and Elio F. Vanin Is) Hemoprotein Oxygen Transport: Models and Mechanism. T. G.Teylor
Most of the reviews appear to have been written in 1976, and some citations are to work published as recently as early 1976. The reviews generally deal with a very specific research problem and emphasize the results and developments from the author's laboratory. Thus, the series is not comprehensive and does nut uniformly cover the field of hioorganic chemistry. Instead, the reviews present the highlights of some of the more exciting work that has been accomplished in
written for the graduate student or professional, several of the reviews would be excellent reading for the undergraduate. One example is the second article in m h n e 111 which reviews research in the possihle chemical events leadine" to the formation of a primordial cell. Many of the authors have written articles in whleh the experimental A184 / Journal of Chemical Education
Using Digital and Analog Integrated Circuits
L. W Shacklette and H. A. Ashworth, Seton Hall University. Prentice-Hall, Inc., Englewood Cliffs, New Jersey, 1978. Figs. & tables. 15 X 22.7 cm x 305 pp. $10.95.
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Shacklette and Ashworth, in their hook, "Using Digital and Analog Integrated Circuits" have provided a very practical primer for any laboratory course which introduces the use of analog or digital "chips." The word "Using" in the title is the key to what their book about. The authors devote 123 pages to digital circuits covering gates, co ole an algebra, buffers, flip-flops, decoders, counters, adders, registers, and memories. In most of the digital topics there are two coverages; one using a T T L and the other a CMOS device. In 88 pages the section covers the operational amplifier, the non-inverting amplifier, integration and differentiation, comparators, Schmitt trigger, the logarithmic amplifier, constant voltage, and current sources, power amolifiers. active filters. and relavs. In hoth
lems. Fifty-six pages are devoted to 12 projects which involve the construction of some practical device ranging from an electronic music box to a multiplexer. Projects are meant t o apply what has been developed already. The 41 pages of appendices cover sources of equipment, data sheets, a glossary and utilitarian circuits for power supplies, and a logic probe. There is a four page index. The authors provide a list of very practical references. Among them are several trade manuals. In the only noteworthy oversight that I could detect Hoenig and Payne's useful hook ("Haw T o Build and Use Electronic Devices Without Frustration, Panic, Mountains of Money or an Engineering Degree, Little") is mentioned in the preface but rrmitted from the reference list, and nowhere does the title and publisher appear. I believe there are three aspects to practical laboratory work with which such a book must deal. First, the experiments, if they are to be done by each student individually or in pairs, must use inexpensive components and the authors must tell how to procure them. The authors do a superlative joh in that. They have addresses of 14 suppliers of cvmponents including the main surplus suppliers. Fur-
thermore, they give frank suggestions about the best sources of components. They are clearly experienced a t procuring cheap parts. Departments with even the most meager budget can include instrumentation with state-of-the-art components with the help of this book. Second, the authors of a laboratary book cannot afford the luxury of going into great theoretical detail. They must have the rare ability to deal concisely and clearly with components in paragraphs or sentences where "theoretical" books use chapters. Othenvise the laboratory work becomes much more time consuming than can he afforded generally. The authors have some excellent exposition. They demonstrate that one can intelligently use an LED or an ap amp without knowing solid state theory or Kirchoffs Laws. Third, the exercises should have some applicability to other subjects. That is, the electronics should not be an end in itself. The chemist could be disappointed in this book since none of the experimentsor projects has a specific chemical application identified. To use it, an instructor will need to exercise some imagination. For example, although analog differentiators, null detectors, and relay controllers are dealt with separately in an understandable way, an automatic titrator is not covered. The authors intend for the text to accompany the second semester of an electronicsfor-scientists course covering discrete components. However, it does not draw heavily from that and could accompany a first semester course if students were already familiar with common test equipment, resistors, capacitors, and perhaps Ohm's Law. I believe the hook is well suited to accompany a junior level lab course in physical or analytical chemistry; however, it will require supplemental resources to deal with specific chemical applications. Frederic D. Tabbun The Evergreen State College
Olympia, Washingfon 98505
Optoacoustic Spectroscopy and Detection
doh-Hon Pan, Editor, Case Western Reserve University. Academic Press, New York, 1977. Figs. & tables. 15 X 23.5 cm. xi 244 pp. $19.00.
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"Optoaeaustie Spectroscopy and Detection" is a text of eight chapters written by nine authors and edited by Joh-Han Pao. Although the general quality of the text makes it a welcome addition to the field, it does fall prey to several weaknesses common to multi-author texts. The major strengths of the text are detailed. well written discussions energy transfer in the sample, and the detccrittn girhr r r d i n n anm*!w wme nre well d ~ t a ~ l cin d Cl12ptcrs I ~ t i r e u m r , and 2 lirrrrlrr and \ \ ' . ~ t r ~ a'l'hr d ~ . d w p n uf w r t r acoustic spectrometers is carefully described and illustrated in Chapter 3 (Dewey) with emohasis on instruments intended for soe-
regions, respectively. The last three chapters cover some of the applications of optoacoustic spectroscopy. Vapor phase applications are discussed first for the infrared region, Chapter 6 (Claspy) and the visible and ultraviolet regions, Chapter 7 (Robin). Finally, the applications to solid state samples is covered in Chapter 8 (Rosenwaig). References a t the end of each chapter include citations through 1976. Retter editing of the individual chapter to remove some of the repititious discussions concerning the basic mechanisms of signal generation and transduction as well as the design of the detector itself would have created space for some of the other topics whieh were not as well covered. For example, the text does not include a rigorous discussion of quantitative analytical data treatment. Although this omission may be due to the youth of the field or to the backgrounds of the authors, most chemists would consider it serious. Further, a t no single point in the text is there a general discussion of the relative merits of optoaeoustie spectroscopy in comparison with other mare conventional forms of spectroscopy. Any recommendations for the usefulness of this book has to be made weighing the strengths and weaknesses of the text. Chemists looking for an introduction to this newer spectroscopy may be disappointed in this text; however, chemists faced with applying this method to a specific problem would he well advised to include the appropriate chapters of this book in their reading lists.
to base any statistical analysis of data, and three chapters are devoted t o a detailed discussion of probability theory, including probability distributions such as the binomial, Poisson, normal, and exponential distribution. For those working with limited sets of experimental points, there are two chapters dealing with the theory and practice of the estimation of the unknown parameters of density or distribution functions and includes a treatment of least squares, method of moments, and the Bayesian method. All the methods are well illustrated with examples. A detailed explanation is provided on the computation of a confidence interval for the unknown parameters. Hypothesis testing is the subject of a separate chapter and deals with formal procedures for testing hypotheses. Subsequent chapters apply these concepts with well illustrated examples to tests an means, variances, and goodness of fit. The tests are restricted mainly to the normal distribution. The goodness of fit tesk address the question as to the validity of whether the selected probability distribution or particular farm of a probability distribution is, in fact, appropriate by examining several procedures for testing how well the data fits the probability distribution in question. For those involved in teaching chemistry laboratories for advanced classes chapters 12-15 should be of particular use in improving one's general background. These chapters discuss the situations where the s t r a i ~ hline t or polynomial is constrained to pass ihrough
the origin'or some other fixed point and includes a detailed presentation of least squares analyses, the need for weighting factors, and demonstrates concrete examples of confidence intervals, inverse interpolation, hypotheses testing, and goodness of fit models. Also included in this book are discussions of rounding-off errors and the choice of the number ofsignificant figures. The text has been produced using a photo-offset method, but it is well organized, clearly presented, and free from any major errors. I t is certainly too expensive for student purchase, but it is not unreasonably priced for acquisition by libraries, and by researchers and teachers who are directly involved with the analysis of data. Reginald P. T. Tomkins Dept, of Chemical Engineering and Chemistry New Jersey Institute of Technology Newark, 077102
Claslcal Kinetic Theory of Fluids
P. Resibois, and M.De Leener Free University-Brussels. John Wiley & Sons, New York, 1977. Figs. 15.5 X 23.5 cm. av 412 pp. $29.50.
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'l'hr .tatrd gual of this work iq to prrsrnr n njhtrmt and witomolnrd inrmdurr~m18, CmI~n~.m ai p w c AlR6J
Dale H Karweik Wayne State Unrvemity Detrort, Mi 48202
Statistical Treatment of Experimental Data
J. R. Green, and D. Margerison, University of Liverpool. Elsevier Scientific Publishing Co., Amsterdam, 1977. Figs. & tables. 15.5 X 23 cm. x 382 pp. $34.95.
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This book presents a rigorous treatment of statistical methods which may be employed to handle experimental data and the extent. to which useful conclusions can be drawn from the data. The coverage is extensive and highly mathematical. Numerous examples of the applications of statistical analysis to typical experimental data sets are provided including a liberal representation fmm several areas of chemistry. The approach adopted in this book is far beyond that required for undergraduate courses in the physical sciences, since selected chapters in most existing textbwks treat this topic adequately. Instructors in physical chemistry laboratory courses would find the text a useful addition to their personal bookshelf, and it is strongly recommended as a reference source for the library. For the researcher who is involved in handling large quantities of data and for those whose orimarv interest is the critical eamoi-
ing data. The authors have stressed the need for assuming some probability model on whieh Volume 56, Number 4, April 71979 / A185
