J . Am. Chem. SOC.1980, 102, 6196-6198
6196
N(1), NH2(6), and N(7) of A M P adenine rings. The bond distances determined from the ISNinvestigation clearly show that the metal-nucleotide ring interaction is an inner-sphere coordination effect. Evidence for two separate binding sites is presented and serves to explain an anomalously short MnZ+-C(8) bond distance. Extension of these multinuclear studies to ISN-enriched nucleotides will allow investigation of 1:1 metal-nucleotide complexes
at physiologically significant nucleotide concentrations,
