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A laboratory scale microbial food chain to study bioaccumulation, biomagnification and ecotoxicity of cadmium telluride quantum dots Govind Sharan Gupta, Ashutosh Kumar, Violet Aileen Senapati, Alok Kumar Pandey, Rishi Shanker, and Alok Dhawan Environ. Sci. Technol., Just Accepted Manuscript • DOI: 10.1021/acs.est.6b03950 • Publication Date (Web): 09 Jan 2017 Downloaded from http://pubs.acs.org on January 10, 2017
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Environmental Science & Technology
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A laboratory scale microbial food chain to study bioaccumulation,
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biomagnification and ecotoxicity of cadmium telluride quantum dots
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Govind S. Gupta1,2, Ashutosh Kumar1, Violet A. Senapati1, Alok K. Pandey2,
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Rishi Shanker1* and Alok Dhawan2*
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Author’s Affiliations: 1
Division of Biological & Life Sciences, School of Arts & Sciences (Formerly, Institute of Life Sciences), Ahmedabad University, University Road, Navrangpura, Ahmedabad - 380009, Gujarat (India) 2
Nanotherapeutics & Nanomaterial Toxicology Group, CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Vishvigyan Bhawan, 31- M.G. Marg, P.O. Box – 80, Lucknow - 226001, U.P. (INDIA)
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ACS Paragon Plus Environment
Environmental Science & Technology
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ABSTRACT
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The increasing applications of engineered nanomaterials (ENMs) in consumer
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products warrant a careful evaluation of their trophic transfer and consequent
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ecological impact. In the present study, a laboratory scale aquatic microbial food
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chain was established using bacteria (Escherichia coli) as a prey and ciliated
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protozoan (Paramecium caudatum) as a predator organism to determine the impact
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of cadmium telluride quantum dots (CdTe QDs). We observed that 29% of
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bacterivory potential of Paramecium was lost, including a ~12 h of delay in doubling
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time on exposure to 25 mg/L of CdTe QD (~4 nm) as compared to control. The
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fluorescence based stoichiometric analysis revealed that 65% of the QDs
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bioaccumulated when paramecia were exposed to 25 mg/L of QDs at 24 h. There
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was a significant (p
