POTASSIUM BOROHYDRIDE PRICE NEWS! New low IVIHI KBH4 prices expand borohydride applications formerly blocked by high costs Great news! M H I potassium borohydride ( K B H 4 ) is now the lowest priced commercially available borohydride r e ducing agent. W h e r e high price m a y h a v e blocked u s e before, many companies now can profit from K B H 4 for faster, easier, higher yield specific reductions of esters, aldehydes, ketones, acid chlorides and acid anhydrides. Newproduction techniques make these new prices possible. I n addition to price advantage, there a r e m a n y other factors which m a k e M H I K B H 4 a uniquely versatile a n d useful reagent. M H I K B H 4 is selective. I t goes straight t o the h e a r t of a specific reduction without side reactions, without affecting other reducible groups present a n d without attacking olefinic bonds. A white crystalline solid with a p u r i t y of 99% and density of 1.175 g/cc, M H I K B H 4 i s stable and can be handled and stored safely in a i r without loss of purity. You can use i t in conventional e q u i p m e n t employing standard techniques.
hydrocarbons. I t h a s a negative heat of solution in water of 6.3 Kcal/mol. All of these unique advantages, plus the new low price m a k e it a good m o v e for you t o use M H I K B H 4 for reactions like t h e s e : TYPICAL ORGANIC REACTIONS: Aldehyde reduction: O 02N-
y-A-"C
OC2H5
112
C&EN
SEPT.
16, 1 9 5 7
KBH 2
-f-
THF v LiCl — - — >
I NO2 Acid chloride reduction: O II CH3CH2CH2C — C I
NO2 (Hydrolysis product)
dioxane - > CH3CH2CH2CH2OH + KBH 2 (Hydrolysis product) GET THE FACTS O N THESE NEW KBH4 PRICES!
Call or write for complete information. Technical assistance is also available without obligation.
PIONEERS
STREET,
- > CH3CHOHC2H5 (Hydrolysis product)
KBH . 4
CK2OH
K
Metal Hydrides CONGRESS
+
Ester reduction:
CHEMICAL
%
•CH2OH
(Hydrolysis product) Ketone reduction: O II CH3C — C2H5
Solubility is 19.3 grams/100 grams water. Other solvents a r e water-methanol mixtures, in which solubility ranges from 13.0 grams/100 grams solvent for a ratio of 4 to 1 water-methanol solution down to 0.7 grams/100 grams solvent for methanol alone. M H I K B H 4 also dissolves i n other water-alcohol mixtures and liquid ammonia. T h e solubility in dimethyl formamide is 1.2 grams/100 grams solvent and in dimethyl sulfoxide is 7.5 grams/100 grams solvent at 25°C. In general, solubility sharply decreases with higher alcohols and i t is generally insoluble in ethers a n d
619
-> O2N— < f _ \
H -f KBH .
HYDRIDE
DIVISION
Incorporated IN HYDROGEN
BEVERLY,
COMPOUNDS
MASSACHUSETTS
